Polysorbate 20
;)
Sorbitan,monododecanoate,poly(oxy-1,2-ethanediyl)derivs.
Polyoxyethylene 20sorbitan monolaurate [9005-64-5].
»Polysorbate 20is a laurate ester of sorbitol and its anhydrides copolymerized with approximately 20moles of ethylene oxide for each mole of sorbitol and sorbitol anhydrides.
Packaging and storage—
Preserve in tight containers.
Identification—
B:
To 2mLof a solution (1in 20)add 0.5mLof bromine TSdropwise:the bromine is not decolorized (distinction from Polysorbate 80).
Hydroxyl value á401ñ:
between 96and 108.
Saponification value á401ñ:
between 40and 50.
Organic volatile impurities,Method IVá467ñ:
meets the requirements.
Other requirements—
It meets the requirements for Water,Residue on ignition,Heavy metals,and Acid valueunder Polysorbate 80.
Auxiliary Information—
Staff Liaison:Justin Lane,B.S.,Scientific Associate
Expert Committee:(EMC)Excipients:Monograph Content
USP28–NF23Page 3063
Phone Number:1-301-816-8323