Neomycin and Polymyxin B Sulfates,Gramicidin,and Hydrocortisone Acetate Cream
»Neomycin and Polymyxin B Sulfates,Gramicidin,and Hydrocortisone Acetate Cream contains the equivalent of not less than 90.0percent and not more than 130.0percent of the labeled amounts of neomycin,polymyxin B,and gramicidin,and not less than 90.0percent and not more than 110.0percent of the labeled amount of hydrocortisone acetate (C23H32O6).
Packaging and storage— Preserve in well-closed containers.
Minimum fill á755ñ: meets the requirements.
Assay for neomycin and Assay for polymyxin B— Proceed with Cream as directed in the Assay for neomycinand in the Assay for polymyxin Bunder Neomycin and Polymyxin B Sulfates and Bacitracin Zinc Ophthalmic Ointment.
Assay for gramicidin— Proceed with Cream as directed in the Assay for gramicidinunder Neomycin Sulfate and Gramicidin Ointment.
Assay for hydrocortisone acetate— Proceed with Cream as directed in the Assayunder Hydrocortisone Acetate Lotion.
Auxiliary Information— Staff Liaison:William W.Wright,Ph.D.,Scientific Fellow
Expert Committee:(PA7)Pharmaceutical Analysis 7
USP28–NF23Page 1358
Pharmacopeial Forum:Volume No.30(2)Page 520
Phone Number:1-301-816-8335