Neomycin and Polymyxin B Sulfates and Gramicidin Cream, chemical structure, molecular formula, Reference Standards

Neomycin and Polymyxin B Sulfates and Gramicidin Cream

»Neomycin and Polymyxin B Sulfates and Gramicidin Cream contains the equivalent of not less than 90.0percent and not more than 130.0percent of the labeled amounts of neomycin,polymyxin B,and gramicidin.

Packaging and storage— Preserve in collapsible tubes or in well-closed containers.

USP Reference standards á11ñ— USP Gramicidin RS.USP Neomycin Sulfate RS.USP Polymyxin B Sulfate RS.

Minimum fill á755ñ: meets the requirements.

Assay for neomycin and Assay for polymyxin B— Proceed with Cream as directed in the Assay for neomycinand in the Assay for polymyxin Bunder Neomycin and Polymyxin B Sulfates and Bacitracin Zinc Ophthalmic Ointment.

Assay for gramicidin— Proceed with Cream as directed in the Assay for gramicidinunder Neomycin Sulfate and Gramicidin Ointment.

Auxiliary Information— Staff Liaison:William W.Wright,Ph.D.,Scientific Fellow

Expert Committee:(PA7)Pharmaceutical Analysis 7

USP28–NF23Page 1357

Phone Number:1-301-816-8335