Ferrous Sulfate Syrup
»Ferrous Sulfate Syrup contains,in each 100mL,not less than 3.75g and not more than 4.25g of ferrous sulfate (FeSO4·7H2O),equivalent to not less than 0.75g and not more than 0.85g of elemental iron.
Ferrous Sulfate 40g
Citric Acid,hydrous 2.1g
Peppermint Spirit 2mL
Sucrose 825g
Purified Water,a sufficient quantity,
to make		 1000mL
Dissolve the Ferrous Sulfate,the Citric Acid,the Peppermint Spirit,and 200g of the Sucrose in 450mLof Purified Water,and filter the solution until clear.Dissolve the remainder of the Sucrose in the clear filtrate,and add Purified Water to make 1000mL.Mix,and filter,if necessary,through a pledget of cotton.
Packaging and storage— Preserve in tight containers.
Labeling— Label Syrup in terms of the content of ferrous sulfate (FeSO4·7H2O)and in terms of the content of elemental iron.
Identification— Dissolve 1mLof Syrup with water to about 100mL:the solution responds to the tests for Ferrous Salts á191ñand for Sulfate á191ñ.
Assay— Transfer 25mLof Syrup,accurately measured,to a 250-mLconical flask.Add 15mLof 2Nsulfuric acid and 100mLof water,and shake well.Add 3drops of orthophenanthroline TS,and titrate with 0.1Nceric sulfate VS.Perform a blank determination,and make any necessary correction.Each mLof 0.1Nceric sulfate is equivalent to 27.80mg of ferrous sulfate (FeSO4·7H2O).
Auxiliary Information— Staff Liaison:Lawrence Evans,III,Ph.D.,Scientist
Expert Committee:(DSN)Dietary Supplements:Non-Botanicals
USP28–NF23Page 821
Phone Number:1-301-816-8389