C19H24N2O·H2SO4 394.49
a-[2-(Dimethylamino)propyl]-a-phenylbenzeneacetamide sulfate [60-46-8].

Packaging and storage— Preserve in tight containers,and store at controlled room temperature.

Labeling— Label it to indicate that it is for veterinary use only.

USP Reference standards á11ñ— USP Aminopentamide Sulfate RS.

Clarity and color of solution— Dissolve 0.5g in 10mLof water:the solution is clear and colorless.

Identification—

Melting range á741ñ: between 179and 186.

pHá791ñ: between 1.2and 3.0,in a solution (2.5in 100).

Loss on drying á731ñ— Dry it at 105for 4hours:it loses not more than 4.4%of its weight.

Residue on ignition á281ñ: not more than 0.5%.

Assay— Dissolve about 500mg of Aminopentamide Sulfate,accurately weighed,in 100mLof dimethylformamide in a suitable container.Add 5drops of thymol blue TS,and titrate with 0.1Nlithium methoxide VSin benzene to a deep blue endpoint.Perform a blank determination,and make any necessary correction.Each mLof 0.1Nlithium methoxide is equivalent to 19.72mg of C19H24N2O·H2SO4.

Expert Committee:(VET)Veterinary Drugs

USP28–NF23Page 127

Phone Number:1-301-816-8178