Packaging and storage— Preserve in well-closed,light-resistant containers.

Labeling— The label states the Latin binomial and,following the official name,the part of the plant from which the article was derived.

USP Reference standards á11ñ— USP Chlorogenic Acid RS.USP Powdered Echinacea purpurea Extract RS.USP2E,4E-Hexadienoic Acid Isobutylamide RS.

Botanic characteristics— Under a microscope,the following characteristics are observed:vessels (80×30µm)with slanted end walls and spiral or pitted secondary walls;rectangular cork cells (150×60µm)with brown inclusions;rectangular parenchymatous cells (120×30µm),some pitted;elongated fiber cells having a narrow lumen with funnel-shaped end (20to 40µm wide);polygonal sclereids;a melanogenic layer of variable thickness,interspersed between the cell walls of the parenchyma;and lignified sclereids,vessels,and fibers.Starch is present;calcium oxalate and inulin crystals are absent.

Other requirements— It meets the requirements of the tests for Identification,Loss on drying,Total ash,Acid-insoluble ash,Pesticide residues,Heavy metals,Content of total phenols,and Content of alkamidesunder Echinacea purpurea Root.

Expert Committee:(DSB)Dietary Supplements:Botanicals

USP28–NF23Page 2082

Phone Number:1-301-816-8343