Coal Tar Topical Solution
»Prepare Coal Tar Topical Solution as follows.
Coal Tar 200g
Polysorbate 80 50g
Alcohol,a sufficient quantity,
to make
1000mL
Mix the Coal Tar with 500g of washed sand (see under Reagentsin the section Reagents,Indicators,and Solutions),and add the Polysorbate 80and 700mLof Alcohol.Macerate the mixture for 7days in a closed vessel with frequent agitation.Filter,and rinse the vessel and the filter with sufficient Alcohol to make the product measure 1000mL.
Packaging and storage— Preserve in tight containers.
Alcohol content á611ñ: between 81.0%and 86.0%of C2H5OH.
Auxiliary Information— Staff Liaison:Lawrence Evans,III,Ph.D.,Scientist
Expert Committee:(PA6)Pharmaceutical Analysis 6
USP28–NF23Page 528
Phone Number:1-301-816-8389