Packaging and storage— Preserve in well-closed,light-resistant containers,protected from moisture.

Labeling— The label states the Latin binomial and,following the official name,the part of the plant from which the article was derived.

USP Reference standards á11ñ— USP Escin RS.

Botanic characteristics— Yellowish-brown powder,odorless,with a somewhat mealy,disagreeably bitter,and lingering taste.It shows numerous,different-sized fatty oil droplets that are free or within the thin-walled,colorless tissue of the cotyledons.Fragments of the testa consist of thick-walled pitted sclerenchymatous cells.The following are also present:pyriform,roundish or reniform larger individual starch granules from 15to 30µm in diameter,smaller individual granules from 3to 10µm,and only a few compounded granules consisting of 2to 4single grains that form rows up to 45µm in length.Many of the starch granules have a bistellate or polystellate,but rarely simple,hilum.

Other requirements— It meets the requirements of the tests forIdentification,Microbial enumeration,Loss on drying,Extractable matter,Total ash,Pesticide residues,Heavy metals,and Content of triterpene glycosides underHorse Chestnut.

Expert Committee:(DSB)Dietary Supplements:Botanicals

USP28–NF23Page 2108

Phone Number:1-301-816-8343