Packaging and storage— Preserve in well-closed containers,and store at controlled room temperature.

Labeling— The label states the Latin binomial and,following the official name,the part of the plant from which the article was derived.

USP Reference standards á11ñ— USP Agnuside RS.USP Casticin RS.USP Powdered Chaste Tree Extract RS.

Botanic characteristics— Powdered Chaste Tree is dark brown,with a musty,slightly aromatic odor,and a taste resembling that of sage.The following characteristics are present:fragments of the calyx with covering and glandular trichomes on the outer side and rectangular,elongated cells with slightly wavy walls on the inner side;fragments of exocarp with trichomes and cells with large pits in the outer wall;thin-walled parenchymatous cells and globules of fixed oil;stone-pitted cells from the mesocarp;ovoid,lignified cells with bands of reticulate thickening from the testa;and endosperm and cotyledons with fixed oil.

Other requirements— It meets the requirements of the tests for Identification,Microbial enumeration,Loss on drying,Total ash,Acid-insoluble ash,Pesticide residues,Heavy metals,Content of casticin,and Content of agnusideunder Chaste Tree.

Expert Committee:(DSB)Dietary Supplements:Botanicals

USP28–NF23Page 2065

Phone Number:1-301-816-8343