1  Aseries of documents entitled Points to Considerare available from the Director,FDA Center for Biologics Evaluation and Research,HFB-1,8800Rockville Pike,Bethesda,MD20892.

2  This guideline was originally published in the Federal Register,Guidelines for Research Involving Recombinant DNA Molecules1986;51(88):16957-16985.Copies may be obtained from the Office of Recombinant DNA Activities,12441Parklawn Drive,Suite 58,Rockville,MD20852.

3  Acomprehensive guideline,Biosafety in Microbiological and Biomedical Laboratories,is available from the Superintendent of Documents,U.S.Government Printing Office,Washington,DC20402,stock #107-040-000508-3.