Creams are semisolid dosage forms containing one or more drug substances dissolved or dispersed in a suitable base.This term has traditionally been applied to semisolids that possess a relatively fluid consistency formulated as either water-in-oil (e.g.,Cold Cream)or oil-in-water (e.g.,Fluocinolone Acetonide Cream)emulsions.However,more recently the term has been restricted to products consisting of oil-in-water emulsions or aqueous microcrystalline dispersions of long-chain fatty acids or alcohols that are water washable and more cosmetically and aesthetically acceptable.Creams can be used for administering drugs via the vaginal route (e.g.,Triple Sulfa Vaginal Cream).